Recent developments in biochemistry of the plant lipoxygenase pathway

Lipoxygenase (LOX, EC 1.13.11.12) is a dioxygenase enzyme widespread in aerobic organisms, including plants. The enzyme oxygenates methylene interrupted polyenoic fatty acids, converting them into hydroperoxides. The predominant substrates of LOXs in plants are linoleic and linolenic acids. Specificities of LOX action and availability of enzymes of hydroperoxide metabolism detemine the diversity of the LOX pathway products. Increasing evidence in the literature demonstrates the great physiological importantance of the plant LOX pathway products.

Source: Progress in Lipid Research (1998) vol. 37 , p. 317-352